Path‐seq identifies an essential mycolate remodeling program for mycobacterial host adaptation

The success of Mycobacterium tuberculosis (MTB) stems from its ability to remain hidden from the immune system within macrophages. Here, we report a new technology (Path‐seq) to sequence miniscule amounts of MTB transcripts within up to million‐fold excess host RNA. Using Path‐seq and regulatory net...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Peterson, Eliza JR, Bailo, Rebeca, Rothchild, Alissa C, Arrieta‐Ortiz, Mario L, Kaur, Amardeep, Pan, Min, Mai, Dat, Abidi, Abrar A, Cooper, Charlotte, Aderem, Alan, Bhatt, Apoorva, Baliga, Nitin S
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398593/
https://ncbi.nlm.nih.gov/pubmed/30833303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20188584
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