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Simultaneous Quantification of Protein Expression and Modifications by Top-down Targeted Proteomics: A Case of the Sarcomeric Subproteome

Determining changes in protein expression and post-translational modifications (PTMs) is crucial for elucidating cellular signal transduction and disease mechanisms. Conventional antibody-based approaches have inherent problems such as the limited availability of high-quality antibodies and batch-to...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Lin, Ziqing, Wei, Liming, Cai, Wenxuan, Zhu, Yanlong, Tucholski, Trisha, Mitchell, Stanford D., Guo, Wei, Ford, Stephen P., Diffee, Gary M., Ge, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6398208/
https://ncbi.nlm.nih.gov/pubmed/30591534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR118.001086
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