Oxidative modifications of mitochondrial complex II are associated with insulin resistance of visceral fat in obesity

Obesity, particularly visceral adiposity, has been linked to mitochondrial dysfunction and increased oxidative stress, which have been suggested as mechanisms of insulin resistance. The mechanism(s) behind this remains incompletely understood. In this study, we hypothesized that mitochondrial comple...

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Udgivet i:Am J Physiol Endocrinol Metab
Main Authors: Ngo, Doan T. M., Sverdlov, Aaron L., Karki, Shakun, Macartney-Coxson, Donia, Stubbs, Richard S., Farb, Melissa G., Carmine, Brian, Hess, Donald T., Colucci, Wilson S., Gokce, Noyan
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397365/
https://ncbi.nlm.nih.gov/pubmed/30576243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00227.2018
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