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Oxidative modifications of mitochondrial complex II are associated with insulin resistance of visceral fat in obesity

Obesity, particularly visceral adiposity, has been linked to mitochondrial dysfunction and increased oxidative stress, which have been suggested as mechanisms of insulin resistance. The mechanism(s) behind this remains incompletely understood. In this study, we hypothesized that mitochondrial comple...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Ngo, Doan T. M., Sverdlov, Aaron L., Karki, Shakun, Macartney-Coxson, Donia, Stubbs, Richard S., Farb, Melissa G., Carmine, Brian, Hess, Donald T., Colucci, Wilson S., Gokce, Noyan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397365/
https://ncbi.nlm.nih.gov/pubmed/30576243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00227.2018
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