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Forkhead Box O-1 modulation improves endothelial insulin resistance in human obesity

OBJECTIVE: Increased visceral adiposity has been closely linked to insulin resistance, endothelial dysfunction, and cardiometabolic disease in obesity, but pathophysiological mechanisms are poorly understood. We sought to investigate mechanisms of vascular insulin resistance by characterizing depot-...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Karki, Shakun, Farb, Melissa G, Ngo, Doan TM, Myers, Samantha, Puri, Vishwajeet, Hamburg, Naomi M, Carmine, Brian, Hess, Donald T, Gokce, Noyan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441602/
https://ncbi.nlm.nih.gov/pubmed/25908760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.305139
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