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Transportan 10 improves the pharmacokinetics and pharmacodynamics of vancomycin
In the presented study, transportan 10 (TP10), an amphipathic cell penetrating peptide (CPP) with high translocation activity, was conjugated with vancomycin (Van), which is known for poor access to the intracellular bacteria and the brain. The antibacterial activity of the conjugates was tested on...
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| Vydáno v: | Sci Rep |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6397271/ https://ncbi.nlm.nih.gov/pubmed/30824786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40103-w |
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