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Transportan 10 improves the pharmacokinetics and pharmacodynamics of vancomycin
In the presented study, transportan 10 (TP10), an amphipathic cell penetrating peptide (CPP) with high translocation activity, was conjugated with vancomycin (Van), which is known for poor access to the intracellular bacteria and the brain. The antibacterial activity of the conjugates was tested on...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6397271/ https://ncbi.nlm.nih.gov/pubmed/30824786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40103-w |
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