Toll-Like Receptor 4 Activation Promotes Multiple Myeloma Cell Growth and Survival Via Suppression of The Endoplasmic Reticulum Stress Factor Chop

Despite recent biomedical improvements in treating Multiple Myeloma (MM), the disease still remains incurable. Toll like receptors (TLRs) provide a link between innate and adaptive immune responses and hence potentially correlate inflammation to cancer. Although the regulatory role of TLRs in MM has...

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Pubblicato in:Sci Rep
Autori principali: Bagratuni, Tina, Sklirou, Aimilia D., Kastritis, Efstathios, Liacos, Christine Ivy, Spilioti, Christina, Eleutherakis-Papaiakovou, Evangelos, Kanellias, Nikolaos, Gavriatopoulou, Maria, Terpos, Evangelos, Trougakos, Ioannis P., Dimopoulos, Meletios A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397208/
https://ncbi.nlm.nih.gov/pubmed/30824741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39672-7
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