Toll-Like Receptor 4 Activation Promotes Multiple Myeloma Cell Growth and Survival Via Suppression of The Endoplasmic Reticulum Stress Factor Chop

Despite recent biomedical improvements in treating Multiple Myeloma (MM), the disease still remains incurable. Toll like receptors (TLRs) provide a link between innate and adaptive immune responses and hence potentially correlate inflammation to cancer. Although the regulatory role of TLRs in MM has...

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Publicado no:Sci Rep
Main Authors: Bagratuni, Tina, Sklirou, Aimilia D., Kastritis, Efstathios, Liacos, Christine Ivy, Spilioti, Christina, Eleutherakis-Papaiakovou, Evangelos, Kanellias, Nikolaos, Gavriatopoulou, Maria, Terpos, Evangelos, Trougakos, Ioannis P., Dimopoulos, Meletios A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6397208/
https://ncbi.nlm.nih.gov/pubmed/30824741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39672-7
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