Semaphorin 4D correlates with increased bone resorption, hypercalcemia, and disease stage in newly diagnosed patients with multiple myeloma

Multiple myeloma (MM) is characterized by bone destruction due to increased bone resorption and decreased bone formation. Semaphorin 4D (CD100, Sema4D) is expressed by osteoclasts, binds to its receptor Plexin-B1, and acts as a mediator of osteoclast–osteoblast interaction that ultimately inhibits o...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Cancer J
Egile Nagusiak: Terpos, Evangelos, Ntanasis-Stathopoulos, Ioannis, Christoulas, Dimitrios, Bagratuni, Tina, Bakogeorgos, Marios, Gavriatopoulou, Maria, Eleutherakis-Papaiakovou, Evangelos, Kanellias, Nikolaos, Kastritis, Efstathios, Dimopoulos, Meletios A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945651/
https://ncbi.nlm.nih.gov/pubmed/29748532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-018-0075-6
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