ERBB2 and PTPN2 gene copy numbers as prognostic factors in HER2-positive metastatic breast cancer treated with trastuzumab

Trastuzumab has markedly improved the treatment and long-term prognosis of patients with HER2-positive breast cancer. A frequent clinical challenge in patients with relapsing and/or metastatic disease is de novo or acquired trastuzumab resistance, and to date no predictive biomarkers for palliative...

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Veröffentlicht in:Oncol Lett
Hauptverfasser: Ellegård, Sander, Veenstra, Cynthia, Pérez-Tenorio, Gizeh, Fagerström, Victor, Gårsjö, Jon, Gert, Krista, Sundquist, Marie, Malmström, Annika, Wingren, Sten, Elander, Nils O., Hallbeck, Anna-Lotta, Stål, Olle
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2019
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6396168/
https://ncbi.nlm.nih.gov/pubmed/30867772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.9998
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