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Solution Structure of a MYC Promoter G-Quadruplex with 1:6:1 Loop Length
[Image: see text] The important MYC oncogene is deregulated in many cancer cells and comprises one of the most prominent G-quadruplex (G4) forming sequences in its promoter regions, the NHE III(1) motif. Formation of G4s suppresses MYC transcription and can be modulated by drug binding, establishing...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2019
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6396123/ https://ncbi.nlm.nih.gov/pubmed/30842981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b03580 |
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