Self-assembled angiopep-2 modified lipid-poly (hypoxic radiosensitized polyprodrug) nanoparticles delivery TMZ for glioma synergistic TMZ and RT therapy

The addition of temozolomide (TMZ) to radiotherapy (RT) improves survival of patients with glioblastoma (GBM). However, TMZ + RT causes excess toxicity in patients. In this study, we prepared angiopep-2 (A2) modified lipid-poly (hypoxic radiosensitized polyprodrug) nanoparticles for TMZ delivery (A2...

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Dades bibliogràfiques
Publicat a:Drug Deliv
Autors principals: Zong, Zhenkun, Hua, Lei, Wang, Zhen, Xu, Haoyue, Ye, Chengkun, Pan, Bomin, Zhao, Zongren, Zhang, Longzhen, Lu, Jun, Liu, Hongmei, Yu, Rutong
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6394306/
https://ncbi.nlm.nih.gov/pubmed/30744436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1534897
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