IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer

Inflammation affects tumor immune surveillance and resistance to therapy. Here, we show that production of IL1 β in primary breast cancer tumors is linked with advanced disease and originates from tumor-infiltrating CD11c(+) myeloid cells. IL1 β production is triggered by cancer cell membrane-derive...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Cancer Res
Main Authors: Wu, Te-Chia, Xu, Kangling, Martinek, Jan, Young, Robyn R., Banchereau, Romain, George, Joshy, Turner, Jacob, Kim, Kyung In, Zurawski, Sandra, Wang, Xuan, Blankenship, Derek, Brookes, Hannah M., Marches, Florentina, Obermoser, Gerlinde, Lavecchio, Elizabeth, Levin, Maren K., Bae, Sookyoung, Chung, Cheng-Han, Smith, Jennifer L., Cepika, Alma-Martina, Oxley, Kyp L., Snipes, George J., Banchereau, Jacques, Pascual, Virginia, O’Shaughnessy, Joyce, Palucka, A. Karolina
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6391892/
https://ncbi.nlm.nih.gov/pubmed/30012670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0413
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla