Broad influenza-specific CD8(+) T-cell responses in humanized mice vaccinated with influenza virus vaccines

The development of novel human vaccines would be greatly facilitated by the development of in vivo models that permit preclinical analysis of human immune responses. Here, we show that nonobese diabetic severe combined immunodeficiency (NOD/SCID) β(2) microglobulin(−/−) mice, engrafted with human CD...

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Detalhes bibliográficos
Principais autores: Yu, Chun I., Gallegos, Michael, Marches, Florentina, Zurawski, Gerard, Ramilo, Octavio, García-Sastre, Adolfo, Banchereau, Jacques, Palucka, A. Karolina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572794/
https://ncbi.nlm.nih.gov/pubmed/18713944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-157016
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