Broad influenza-specific CD8(+) T-cell responses in humanized mice vaccinated with influenza virus vaccines

The development of novel human vaccines would be greatly facilitated by the development of in vivo models that permit preclinical analysis of human immune responses. Here, we show that nonobese diabetic severe combined immunodeficiency (NOD/SCID) β(2) microglobulin(−/−) mice, engrafted with human CD...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yu, Chun I., Gallegos, Michael, Marches, Florentina, Zurawski, Gerard, Ramilo, Octavio, García-Sastre, Adolfo, Banchereau, Jacques, Palucka, A. Karolina
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2008
Pynciau:
Immunobiology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572794/
https://ncbi.nlm.nih.gov/pubmed/18713944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-157016
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