Reprogramming tumor-infiltrating dendritic cells for CD103(+)CD8(+) mucosal T cell differentiation and breast cancer rejection

Our studies showed that tumor-infiltrating dendritic cells (DC) in breast cancer drive inflammatory T helper 2 (iTh2) cells and protumor inflammation. Here we show that intratumoral delivery of the β-glucan curdlan, a ligand of dectin-1, blocks the generation of iTh2 cells, and prevents breast cance...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wu, Te-Chia, Xu, Kangling, Banchereau, Romain, Marches, Florentina, Yu, Chun I, Martinek, Jan, Anguiano, Esperanza, Pedroza-Gonzalez, Alexander, Snipes, G. Jackson, O’Shaughnessy, Joyce, Nishimura, Stephen, Liu, Yong-Jun, Pascual, Virginia, Banchereau, Jacques, Oh, Sangkon, Palucka, Karolina
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014008/
https://ncbi.nlm.nih.gov/pubmed/24795361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-13-0217
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados