GABA and glutamate neurons in the VTA regulate sleep and wakefulness

We screened for novel circuits in the mouse brain that promote wakefulness. Chemogenetic activation experiments and EEG recordings pointed to glutamatergic/nitrergic (NOS1) and GABAergic neurons in the VTA. Activating glutamatergic/NOS1 neurons, which were wake- and REM-sleep-active, produced wakefu...

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Bibliografiset tiedot
Julkaisussa:Nat Neurosci
Päätekijät: Yu, Xiao, Li, Wen, Ma, Ying, Tossell, Kyoko, Harris, Julia J., Harding, Edward C., Ba, Wei, Miracca, Giulia, Wang, Dan, Li, Long, Guo, Juan, Chen, Ming, Li, Yuqi, Yustos, Raquel, Vyssotski, Alexei L., Burdakov, Denis, Yang, Qianzi, Dong, Hailong, Franks, Nicholas P., Wisden, William
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6390936/
https://ncbi.nlm.nih.gov/pubmed/30559475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0288-9
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