Mutations in Efflux Pump Rv1258c (Tap) Cause Resistance to Pyrazinamide, Isoniazid, and Streptomycin in M. tuberculosis

Although drug resistance in Mycobacterium tuberculosis is mainly caused by mutations in drug activating enzymes or drug targets, there is increasing interest in the possible role of efflux in causing drug resistance. Previously, efflux genes have been shown to be upregulated upon drug exposure or im...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Microbiol
Päätekijät: Liu, Jiayun, Shi, Wanliang, Zhang, Shuo, Hao, Xiaoke, Maslov, Dmitry A., Shur, Kirill V., Bekker, Olga B., Danilenko, Valery N., Zhang, Ying
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019
Aiheet:
Microbiology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6389670/
https://ncbi.nlm.nih.gov/pubmed/30837962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.00216
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