Investigation of the Rv3065, Rv2942, Rv1258c, Rv1410c, and Rv2459 efflux pump genes expression among multidrug-resistant Mycobacterium tuberculosis clinical isolates

BACKGROUND: Different resistance mechanisms for multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) have been reported. Although mutations in target genes are the main cause of drug resistance, efflux pumps (Eps) also play an important role in this process....

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Udgivet i:Heliyon
Main Authors: Shahi, Fatemeh, Khosravi, Azar Dokht, Tabandeh, Mohammad Reza, Salmanzadeh, Shokrollah
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318855/
https://ncbi.nlm.nih.gov/pubmed/34337183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2021.e07566
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