Human Brain Endothelial CXCR2 is Inflammation-Inducible and Mediates CXCL5- and CXCL8-Triggered Paraendothelial Barrier Breakdown

Chemokines (C-X-C) motif ligand (CXCL) 5 and 8 are overexpressed in patients with multiple sclerosis, where CXCL5 serum levels were shown to correlate with blood–brain barrier dysfunction as evidenced by gadolinium-enhanced magnetic resonance imaging. Here, we studied the potential role of CXCL5/CXC...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Haarmann, Axel, Schuhmann, Michael K., Silwedel, Christine, Monoranu, Camelia-Maria, Stoll, Guido, Buttmann, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387364/
https://ncbi.nlm.nih.gov/pubmed/30704100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030602
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