Novel insights into neuroinflammation: bacterial lipopolysaccharide, tumor necrosis factor α, and Ureaplasma species differentially modulate atypical chemokine receptor 3 responses in human brain microvascular endothelial cells

BACKGROUND: Atypical chemokine receptor 3 (ACKR3, synonym CXCR7) is increasingly considered relevant in neuroinflammatory conditions, in which its upregulation contributes to compromised endothelial barrier function and may ultimately allow inflammatory brain injury. While an impact of ACKR3 has bee...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Silwedel, Christine, Speer, Christian P., Haarmann, Axel, Fehrholz, Markus, Claus, Heike, Buttmann, Mathias, Glaser, Kirsten
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966865/
https://ncbi.nlm.nih.gov/pubmed/29792190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1170-0
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