Exosomal Expression of CXCR4 Targets Cardioprotective Vesicles to Myocardial Infarction and Improves Outcome after Systemic Administration

Cell therapy has been evaluated to enhance heart function after injury. Delivered cells mostly act via paracrine mechanisms, including secreted growth factors, cytokines, and vesicles, such as exosomes (Exo). Intramyocardial injection of cardiac-resident progenitor cells (CPC)-derived Exo reduced sc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Ciullo, Alessandra, Biemmi, Vanessa, Milano, Giuseppina, Bolis, Sara, Cervio, Elisabetta, Fertig, Emanuel Tudor, Gherghiceanu, Mihaela, Moccetti, Tiziano, Camici, Giovanni G., Vassalli, Giuseppe, Barile, Lucio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386845/
https://ncbi.nlm.nih.gov/pubmed/30678240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030468
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