Exosomal Expression of CXCR4 Targets Cardioprotective Vesicles to Myocardial Infarction and Improves Outcome after Systemic Administration

Cell therapy has been evaluated to enhance heart function after injury. Delivered cells mostly act via paracrine mechanisms, including secreted growth factors, cytokines, and vesicles, such as exosomes (Exo). Intramyocardial injection of cardiac-resident progenitor cells (CPC)-derived Exo reduced sc...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ciullo, Alessandra, Biemmi, Vanessa, Milano, Giuseppina, Bolis, Sara, Cervio, Elisabetta, Fertig, Emanuel Tudor, Gherghiceanu, Mihaela, Moccetti, Tiziano, Camici, Giovanni G., Vassalli, Giuseppe, Barile, Lucio
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386845/
https://ncbi.nlm.nih.gov/pubmed/30678240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030468
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