Inflammatory extracellular vesicles prompt heart dysfunction via TRL4-dependent NF-κB activation

Background: After myocardial infarction, necrotic cardiomyocytes release damage-associated proteins that stimulate innate immune pathways and macrophage tissue infiltration, which drives inflammation and myocardial remodeling. Circulating inflammatory extracellular vesicles play a crucial role in th...

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Publicat a:Theranostics
Autors principals: Biemmi, Vanessa, Milano, Giuseppina, Ciullo, Alessandra, Cervio, Elisabetta, Burrello, Jacopo, Dei Cas, Michele, Paroni, Rita, Tallone, Tiziano, Moccetti, Tiziano, Pedrazzini, Giovanni, Longnus, Sarah, Vassalli, Giuseppe, Barile, Lucio
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052909/
https://ncbi.nlm.nih.gov/pubmed/32194834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.39072
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