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Magnesium-sensitive upstream ORF controls PRL phosphatase expression to mediate energy metabolism

Phosphatases of regenerating liver (PRL-1, PRL-2, and PRL-3, also known as PTP4A1, PTP4A2, and PTP4A3) control magnesium homeostasis through an association with the CNNM magnesium transport regulators. Although high PRL levels have been linked to cancer progression, regulation of their expression is...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hardy, Serge, Kostantin, Elie, Wang, Shan Jin, Hristova, Tzvetena, Galicia-Vázquez, Gabriela, Baranov, Pavel V., Pelletier, Jerry, Tremblay, Michel L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386685/
https://ncbi.nlm.nih.gov/pubmed/30718434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815361116
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