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PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3

The phosphatases of regenerating liver (PRLs) are involved in tumorigenesis and metastatic cancer yet their cellular function remains unclear. Recent reports have shown PRL phosphatases bind tightly to the CNNM family of membrane proteins to regulate magnesium efflux. Here, we characterize the inter...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Zhang, Huizhi, Kozlov, Guennadi, Li, Xinlu, Wu, Howie, Gulerez, Irina, Gehring, Kalle
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427921/
https://ncbi.nlm.nih.gov/pubmed/28246390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00147-2
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