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PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3

The phosphatases of regenerating liver (PRLs) are involved in tumorigenesis and metastatic cancer yet their cellular function remains unclear. Recent reports have shown PRL phosphatases bind tightly to the CNNM family of membrane proteins to regulate magnesium efflux. Here, we characterize the inter...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Zhang, Huizhi, Kozlov, Guennadi, Li, Xinlu, Wu, Howie, Gulerez, Irina, Gehring, Kalle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427921/
https://ncbi.nlm.nih.gov/pubmed/28246390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00147-2
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