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PRL3 phosphatase active site is required for binding the putative magnesium transporter CNNM3

The phosphatases of regenerating liver (PRLs) are involved in tumorigenesis and metastatic cancer yet their cellular function remains unclear. Recent reports have shown PRL phosphatases bind tightly to the CNNM family of membrane proteins to regulate magnesium efflux. Here, we characterize the inter...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Zhang, Huizhi, Kozlov, Guennadi, Li, Xinlu, Wu, Howie, Gulerez, Irina, Gehring, Kalle
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427921/
https://ncbi.nlm.nih.gov/pubmed/28246390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00147-2
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