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IRF5 and IRF8 modulate the CAL-1 human plasmacytoid dendritic cell line response following TLR9 ligation

Synthetic oligonucleotides (ODNs) containing CpG motifs stimulate human plasmacytoid dendritic cells (pDCs) to produce type-1 interferons (IFNs) and proinflammatory cytokines. Previous studies demonstrated that interferon regulatory factors (IRFs) play a central role in mediating CpG-induced pDC act...

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Foilsithe in:Eur J Immunol
Main Authors: Steinhagen, Folkert, Rodriguez, Luis G., Tross, Debra, Tewary, Poonam, Bode, Christian, Klinman, Dennis M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385590/
https://ncbi.nlm.nih.gov/pubmed/26613957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545911
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