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Synergistic Stimulation with Different TLR7 Ligands Modulates Gene Expression Patterns in the Human Plasmacytoid Dendritic Cell Line CAL-1

Objective. TLR7 ligation in plasmacytoid dendritic cells is promising for the treatment of cancer, allergy, and infectious diseases; however, high doses of ligands are required. We hypothesized that the combination of structurally different TLR7 ligands exponentiates the resulting immune response. M...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Hilbert, Tobias, Steinhagen, Folkert, Weisheit, Christina, Baumgarten, Georg, Hoeft, Andreas, Klaschik, Sven
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684865/
https://ncbi.nlm.nih.gov/pubmed/26770023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/948540
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