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Inflammation-induced hypoparathyroidism triggered by combination immune checkpoint blockade for melanoma

BACKGROUND: Treatment with a combination of PD-1 and CTLA-4 targeted checkpoint inhibition has improved outcome of melanoma patients and led to durable remissions but is also associated with significant toxicities. Endocrinopathies such as thyroiditis and hypophysitis are often seen, but other, rare...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Trinh, Beckey, Sanchez, Guacimara Ortega, Herzig, Petra, Läubli, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385398/
https://ncbi.nlm.nih.gov/pubmed/30791949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0528-x
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