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Identification and characterization of a factor Va-binding site on human prothrombin fragment 2
The fragment 2 domain (F2) of prothrombin and its interaction with factor (F) Va is known to contribute significantly to prothrombinase-catalyzed activation of prothrombin. The extent to which the F2-FVa interaction affects the overall thrombin generation, however, is uncertain. To study this intera...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6385242/ https://ncbi.nlm.nih.gov/pubmed/30792421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38857-4 |
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