BRAF V600E and SRC mutations as molecular markers for predicting prognosis and conversion surgery in Stage IV colorectal cancer

Comprehensive genomic sequencing (CGS) enables us to detect numerous genetic alterations in a single assay. We aimed to identify molecular markers for predicting prognosis and conversion surgery in Stage IV colorectal cancer (CRC) using CGS. One-hundred eleven patients with Stage IV CRC who underwen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shimada, Yoshifumi, Muneoka, Yusuke, Nagahashi, Masayuki, Ichikawa, Hiroshi, Tajima, Yosuke, Hirose, Yuki, Ando, Takuya, Nakano, Masato, Sakata, Jun, Kameyama, Hitoshi, Takii, Yasumasa, Ling, Yiwei, Okuda, Shujiro, Takabe, Kazuaki, Wakai, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384937/
https://ncbi.nlm.nih.gov/pubmed/30792536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39328-6
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