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An intact model for quantifying functional selectivity

A ligand that acts on a target receptor to activate particular multiple signalling pathways with activity that is distinct from other ligands is termed ligand bias. Quantification of ligand bias is based on applying the operational model to each pathway separately and subsequent calculation of the l...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Zhu, Xiao, Finlay, David B., Glass, Michelle, Duffull, Stephen B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384912/
https://ncbi.nlm.nih.gov/pubmed/30796256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39000-z
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