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An intact model for quantifying functional selectivity
A ligand that acts on a target receptor to activate particular multiple signalling pathways with activity that is distinct from other ligands is termed ligand bias. Quantification of ligand bias is based on applying the operational model to each pathway separately and subsequent calculation of the l...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6384912/ https://ncbi.nlm.nih.gov/pubmed/30796256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39000-z |
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