An automated microliter-scale high-throughput screening system (MSHTS) for real-time monitoring of protein aggregation using quantum-dot nanoprobes

Protein aggregation is the principal component of numerous protein misfolding pathologies termed proteinopathies, such as Alzheimer’s disease, Parkinson’s disease, prion disease, and AA amyloidosis with unmet treatment needs. Protein aggregation inhibitors have great potential for the prevention and...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Sasaki, Rina, Tainaka, Reina, Ando, Yuichi, Hashi, Yurika, Deepak, Hadya V., Suga, Yoshiko, Murai, Yuta, Anetai, Masaki, Monde, Kenji, Ohta, Kiminori, Ito, Ikuko, Kikuchi, Haruhisa, Oshima, Yoshiteru, Endo, Yasuyuki, Nakao, Hitomi, Sakono, Masafumi, Uwai, Koji, Tokuraku, Kiyotaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384891/
https://ncbi.nlm.nih.gov/pubmed/30796247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38958-0
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