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Real-Time Imaging and Quantification of Amyloid-β Peptide Aggregates by Novel Quantum-Dot Nanoprobes

BACKGROUND: Protein aggregation plays a major role in the pathogenesis of neurodegenerative disorders, such as Alzheimer's disease. However, direct real-time imaging of protein aggregation, including oligomerization and fibrillization, has never been achieved. Here we demonstrate the preparatio...

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Detalhes bibliográficos
Main Authors: Tokuraku, Kiyotaka, Marquardt, Meg, Ikezu, Tsuneya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794548/
https://ncbi.nlm.nih.gov/pubmed/20041162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008492
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