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A Microliter-Scale High-throughput Screening System with Quantum-Dot Nanoprobes for Amyloid-β Aggregation Inhibitors

The aggregation of amyloid β protein (Aβ) is a key step in the pathogenesis of Alzheimer’s disease (AD), and therefore inhibitory substances for Aβ aggregation may have preventive and/or therapeutic potential for AD. Here we report a novel microliter-scale high-throughput screening system for Aβ agg...

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Detalhes bibliográficos
Main Authors: Ishigaki, Yukako, Tanaka, Hiroyuki, Akama, Hiroaki, Ogara, Toshiki, Uwai, Koji, Tokuraku, Kiyotaka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753230/
https://ncbi.nlm.nih.gov/pubmed/23991168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072992
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