Novel Approach for the Search for Chemical Scaffolds with Activity at Both Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor: A Perspective on Scaffolds with Dual Activity for the Treatment of Neurodegenerative Disorders

Neurodegenerative disorders, including Alzheimer’s disease, belong to the group of the most difficult and challenging conditions with very limited treatment options. Attempts to find new drugs in most cases fail at the clinical stage. New tactics to develop better drug candidates to manage these dis...

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Publicado en:Molecules
Main Authors: Kowal, Natalia M., Indurthi, Dinesh C., Ahring, Philip K., Chebib, Mary, Olafsdottir, Elin S., Balle, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384821/
https://ncbi.nlm.nih.gov/pubmed/30691196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24030446
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