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Hantavirus RdRp Requires a Host Cell Factor for Cap Snatching
The hantavirus RNA-dependent RNA polymerase (RdRp) snatches 5′ capped mRNA fragments from the host cell transcripts and uses them as primers to initiate transcription and replication of the viral genome in the cytoplasm of infected cells. Hantavirus nucleocapsid protein (N protein) binds to the 5′ c...
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| Publicado no: | J Virol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6384069/ https://ncbi.nlm.nih.gov/pubmed/30541836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02088-18 |
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