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LATS1/2 kinases trigger self-renewal of cancer stem cells in aggressive oral cancer

Cancer stem cells (CSCs), which play important roles in tumor initiation and progression, are resistant to many types of therapies. However, the regulatory mechanisms underlying CSC-specific properties, including self-renewal, are poorly understood. Here, we found that LATS1/2, the core Hippo pathwa...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Nozaki, Masami, Yabuta, Norikazu, Fukuzawa, Moe, Mukai, Satomi, Okamoto, Ayumi, Sasakura, Towa, Fukushima, Kohshiro, Naito, Yoko, Longmore, Gregory D., Nojima, Hiroshi
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383686/
https://ncbi.nlm.nih.gov/pubmed/30800215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26583
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