ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation

Atherosclerosis, a disease of blood vessels, is driven by cholesterol accumulation and inflammation. Gene therapy that removes cholesterol from blood vessels and decreases inflammation is a promising approach for prevention and treatment of atherosclerosis. In previous work, we reported that helper-...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Stamatikos, Alexis, Dronadula, Nagadhara, Ng, Philip, Palmer, Donna, Knight, Ethan, Wacker, Bradley K., Tang, Chongren, Kim, Francis, Dichek, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383573/
https://ncbi.nlm.nih.gov/pubmed/30079772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2018.120
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