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Apolipoprotein A-I Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits

OBJECTIVE: Gene therapy that expresses apolipoprotein (apo) A-I from vascular wall cells has promise for preventing and reversing atherosclerosis. Previously, we reported that transduction of carotid artery endothelial cells with a helper-dependent adenoviral vector (HDAd) expressing apo A-I reduced...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Wacker, Bradley K., Dronadula, Nagadhara, Bi, Lianxiang, Stamatikos, Alexis, Dichek, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746433/
https://ncbi.nlm.nih.gov/pubmed/29122817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309565
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