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The Evolution of Tumor Formation in Humans and Mice with Inherited Mutations in the p53 Gene

While tumors are very heterogeneous in their origins, mutations in the p53 gene and inactivation of p53 gene functions are the most common feature that predispose to the formation of cancers in humans. Inherited p53 mutations lead to different tumor types at very different frequencies and at very di...

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Detalhes bibliográficos
Publicado no:Curr Top Microbiol Immunol
Autor principal: Levine, Arnold J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383363/
https://ncbi.nlm.nih.gov/pubmed/28349284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2017_5
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