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CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells

Developing tumors interact with the surrounding microenvironment. Myeloid cells exert both anti- and pro-tumor functions and chemokines are known to drive immune cell migration towards cancer cells. It is documented that CXCR4 signaling supports tumor metastasis formation in tissues where CXCL12, it...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Tulotta, C., Stefanescu, C., Chen, Q., Torraca, V., Meijer, A. H., Snaar-Jagalska, B. E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382824/
https://ncbi.nlm.nih.gov/pubmed/30787324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-38643-2
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