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Multi-Substrate Specificity and the Evolutionary Basis for Interdependence in tRNA Editing and Methylation Enzymes

Among tRNA modification enzymes there is a correlation between specificity for multiple tRNA substrates and heteromultimerization. In general, enzymes that modify a conserved residue in different tRNA sequences adopt a heterodimeric structure. Presumably, such changes in the oligomeric state of enzy...

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Bibliografiska uppgifter
I publikationen:Front Genet
Huvudupphovsmän: Dixit, Sameer, Henderson, Jeremy C., Alfonzo, Juan D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382703/
https://ncbi.nlm.nih.gov/pubmed/30838029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00104
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