Gα(i2) signaling regulates inflammasome priming and cytokine production by biasing macrophage phenotype determination

Macrophages exist as innate immune subsets that exhibit phenotypic heterogeneity and functional plasticity. Their phenotypes are dictated by inputs from the tissue microenvironment. G-protein coupled receptors (GPCRs) are essential in transducing signals from the microenvironment, and heterotrimeric...

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Bibliographic Details
Published in:J Immunol
Main Authors: Vural, Ali, Nabar, Neel R., Hwang, Il-Young, Sohn, Silke, Park, Chung, Karlsson, Mikael C. I., Blumer, Joe B., Kehrl, John H.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382563/
https://ncbi.nlm.nih.gov/pubmed/30683698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801145
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