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Gα(i2) signaling regulates inflammasome priming and cytokine production by biasing macrophage phenotype determination
Macrophages exist as innate immune subsets that exhibit phenotypic heterogeneity and functional plasticity. Their phenotypes are dictated by inputs from the tissue microenvironment. G-protein coupled receptors (GPCRs) are essential in transducing signals from the microenvironment, and heterotrimeric...
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| Veröffentlicht in: | J Immunol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6382563/ https://ncbi.nlm.nih.gov/pubmed/30683698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801145 |
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