Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo

Outer membrane vesicles (OMVs) are proteoliposomes blebbed from the surface of Gram-negative bacteria. Chronic periodontitis is associated with an increase in subgingival plaque of Gram-negative bacteria, Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia. In this study, we inve...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Cecil, Jessica D., O’Brien-Simpson, Neil M., Lenzo, Jason C., Holden, James A., Singleton, William, Perez-Gonzalez, Alexis, Mansell, Ashley, Reynolds, Eric C.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574916/
https://ncbi.nlm.nih.gov/pubmed/28890719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01017
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