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AKT regulates NLRP3 inflammasome activation by phosphorylating NLRP3 serine 5
The cytosolic pattern recognition receptor NLRP3 senses host-derived danger signals and certain microbe-derived products in both humans and rodents. NLRP3 activation assembles an inflammasome complex, which contains the adapter protein ASC and caspase-1, whose activation triggers the maturation and...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7541779/ https://ncbi.nlm.nih.gov/pubmed/32929041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000649 |
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