CD44 is a RAS/STAT5-regulated invasion receptor that triggers disease expansion in advanced mastocytosis

The Hermes receptor CD44 is a multifunctional adhesion molecule that plays an essential role in the homing and invasion of neoplastic stem cells in various myeloid malignancies. Although mast cells (MCs) reportedly express CD44, little is known about the regulation and function of this receptor in n...

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Veröffentlicht in:Blood
Hauptverfasser: Mueller, Niklas, Wicklein, Daniel, Eisenwort, Gregor, Jawhar, Mohamad, Berger, Daniela, Stefanzl, Gabriele, Greiner, Georg, Boehm, Alexandra, Kornauth, Christoph, Muellauer, Leonhard, Sehner, Susanne, Hoermann, Gregor, Sperr, Wolfgang R., Staber, Philipp B., Jaeger, Ulrich, Zuber, Johannes, Arock, Michel, Schumacher, Udo, Reiter, Andreas, Valent, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382065/
https://ncbi.nlm.nih.gov/pubmed/30018080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-02-833582
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