Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses

The current influenza vaccine has the inevitable risk of antigenic discordance between the vaccine and the circulating strains, which diminishes vaccine efficacy. This necessitates new approaches that provide broader protection against influenza. Here, we design a vaccine utilizing the hypervariable...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Immunol
Main Authors: Kanekiyo, Masaru, Joyce, M. Gordon, Gillespie, Rebecca A., Gallagher, John R., Andrews, Sarah F., Yassine, Hadi M., Wheatley, Adam K., Fisher, Brian E., Ambrozak, David R., Creanga, Adrian, Leung, Kwanyee, Yang, Eun Sung, Boyoglu-Barnum, Seyhan, Georgiev, Ivelin S., Tsybovsky, Yaroslav, Prabhakaran, Madhu S., Andersen, Hanne, Kong, Wing-Pui, Baxa, Ulrich, Zephir, Kathryn L., Ledgerwood, Julie E., Koup, Richard A., Kwong, Peter D., Harris, Audray K., McDermott, Adrian B., Mascola, John R., Graham, Barney S.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380945/
https://ncbi.nlm.nih.gov/pubmed/30742080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0305-x
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki