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Developmental regulation of DNA cytosine methylation at the immunoglobulin heavy chain constant locus
DNA cytosine methylation is involved in the regulation of gene expression during development and its deregulation is often associated with disease. Mammalian genomes are predominantly methylated at CpG dinucleotides. Unmethylated CpGs are often associated with active regulatory sequences while methy...
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| Publié dans: | PLoS Genet |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6380546/ https://ncbi.nlm.nih.gov/pubmed/30779742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007930 |
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